Isolation of differentially expressed genes in human heart tissues

identification of differentially expressed genes in l02 human hepatocyte induced by hepatitis c virus core protein

Isolation of differentially expressed sequence tags from human breast cancer.

Identification of quantitative changes in gene expression that occur in the malignant mammary gland, if sufficiently characterized, may yield novel molecular markers which may be useful in the diagnosis and treatment of human breast cancer. Using modifications of a previously documented technique, the differential display polymerase chain reaction, we describe the isolation of differentially ex...

Differentially Expressed Genes and Signature Pathways of Human Prostate Cancer

Genomic technologies including microarrays and next-generation sequencing have enabled the generation of molecular signatures of prostate cancer. Lists of differentially expressed genes between malignant and non-malignant states are thought to be fertile sources of putative prostate cancer biomarkers. However such lists of differentially expressed genes can be highly variable for multiple reaso...

Finding Significantly Differentially Expressed Genes

Scientists are interested in how gene expression levels may vary under different treatments. They want to know which genes are expressed differently under treatment conditions and control conditions. Gene expression microarray data are modeled to find significant changes in gene expression levels between a control and treatment tissue co-hybridized on one slide. The model used is the Bayesian h...

Hunting for differentially expressed genes.

Differentially expressed genes are usually identified by comparing steady-state mRNA concentrations. Several methods have been used for this purpose, including differential hybridization, cDNA subtraction, differential display and, more recently, DNA chips. Subtractive hybridization has significantly improved after the polymerase chain reaction was incorporated into the original method and many...